These scripts are described in Posthuma D, Geus EJC de, Boomsma DI, and Neale MC. (2004). Combined linkage and association tests in Mx. Behavior Genetics, 34(1). Paper will be available online in 2003 MxSite.zip: Zipfile of all the following files. example.dat: Example data file CombLinkAssoNoParents.mx Mx script to evaluate significance of association, without using parental genotypes Datagroups: MZ DZ Evaluated models: 1. Full Model: AEQ + grand mean, age effect, sex effect, additive association within, additive association between, dominance association within, dominance association between 2. Test for linkage in presence of association: AE + grand mean, age effect, sex effect, additive association within, additive association between, dominance association within, dominance association between 3. Test for population stratification: AE + grand mean, age effect, sex effect, additive association within = additive association between, dominance association within = dominance association between 4. Test for dominance: AE + grand mean, age effect, sex effect, additive association within = additive association between, no dominance 5. Test for association: AE + grand mean, age effect, sex effect 6. Test for linkage in absence of association: AEQ + grand mean, age effect, sex effect CombLinkAssoParents.mx Mx script to evaluate significance of association, using parental genotypes Datagroups: MZ DZ (+parental genotypes, not parental phenotypes) Evaluated models: 1. Full Model: AEQ + grand mean, age effect, sex effect, additive association within, additive association between, dominance association within, dominance association between 2. Test for linkage in presence of association: AE + grand mean, age effect, sex effect, additive association within, additive association between, dominance association within, dominance association between 3. Test for population stratification: AE + grand mean, age effect, sex effect, additive association within = additive association between, dominance association within = dominance association between 4. Test for dominance: AE + grand mean, age effect, sex effect, additive association within = additive association between, no dominance 5. Test for association: AE + grand mean, age effect, sex effect 6. Test for linkage in absence of association: AEQ + grand mean, age effect, sex effect